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The kidneys have difficulty filtering the myoglobin out of the
bloodstream, because it blocks the structures within the kidney,
which can result in serious kidney damage or kidney failure.
Additionally, the dead skeletal muscle can cause large shifts
in fluid from the bloodstream into the muscle, which reduces
the relative fluid volume of the body and can lead to shock and
reduced blood flow to the kidneys.
Rhabdomyolysis affects about one out of
10,000 people in the United States, with slighter higher incidence
in men. Rhabdomyolysis accounts for an estimated eight to fifteen
percent of cases of acute renal failure. About five percent of
rhabdomyolysis cases result in death.
Myositis | Causes
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